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Symbol
Name
ID

Vhl
von Hippel-Lindau tumor suppressor
MGI:103223

Phenotype annotations related to liver/biliary system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Hepatic hemangioma	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver
Disease(s) Associated with VHL	Hepatosplenomegaly	Hepatic hemangioma	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver
pancreatic cancer
von Hippel-Lindau disease

Mouse Phenotypes		liver/biliary system phenotype	focal hepatic necrosis	increased hepatocyte proliferation	enlarged liver	increased liver weight	abnormal liver morphology	abnormal hepatocyte morphology	hepatic steatosis	increased hepatic hemangioma incidence
Availability	Mouse Genotype	liver/biliary system phenotype	focal hepatic necrosis	increased hepatocyte proliferation	enlarged liver	increased liver weight	abnormal liver morphology	abnormal hepatocyte morphology	hepatic steatosis	increased hepatic hemangioma incidence
	Vhl^tm1.1Whkr/Vhl^tm1.1Whkr	*
	Vhl^tm1Mcs/Vhl^tm1Mcs
	Vhl^tm1.1Jae/Vhl⁺
	Vhl^tm1.1Lss/Vhl⁺
	Vhl^tm1.1Wkr/Vhl⁺	*
	Vhl^tm1Lss/Vhl^tm1.1Lss
	Vhl^tm1Jae/Vhl^tm1Jae Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)
	Hprt1^{tm1(Pck1-cre)Vhh}/Y Vhl^tm1Jae/Vhl^tm1Jae (conditional)
	Vhl^tm1Lss/Vhl^tm1.1Lss Tg(ACTB-cre)1Tes/0 (conditional)
	Vhl^tm1Lss/Vhl^tm1.1Lss Tg(CAG-cre/Esr1*)1Lbe/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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